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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Mitochondrial fusion ： ウィキペディア英語版 Mitochondrial fusion Mitochondrial fusion is a process mediated by several large GTPases whose combined effects lead to the dynamic mitochondrial networks seen in many cell types. Mitochondria are dynamic organelles with the ability to fuse (fusion) and divide (fission), forming constantly changing tubular networks in most eukaryotic cells. The regulation of mitochondrial dynamics is crucial for the health of the cell. Defects in these dynamics are directly associated with numerous genetic disorders. Through mitochondrial fusion, these organelles can overcome the dangerous consequences of genetic malfunction. The process of mitochondrial fusion incorporates a variety of proteins, which assist the cell throughout the series of events that form this specific process. ==Mitochondrial fusion process overview== When cells experience metabolic or environmental stresses, mitochondrial fusion and fission work to maintain functional mitochondria. An increase in fusion activity leads to mitochondrial elongation, whereas an increase in fission activity results in mitochondrial fragmentation. The components of this process can influence programmed cell death and lead to neurodegenerative disorders such as Parkinson's disease. Such cell death can be caused by disruptions in the process of either fusion or fission. The shape of mitochondria are continually changing through the combination of fission, fusion, and motility. Specifically, fusion assists in modifying stress by integrating the contents of slightly damaged mitochondria as a form of complementation. By enabling genetic complementation, fusion of the mitochondria allows for two mitochondrial genomes with different defects within the same organelle to individually encode what the other lacks. In doing so, these mitochondrial genomes generate all of the necessary components for a functional mitochondrion.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Mitochondrial fusion」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.